Metatarsalgia is a general term for pain in the ball of the foot (the metatarsal heads, the bony region just behind the toes). It is a symptom rather than a specific diagnosis, and identifying the underlying cause is essential for appropriate treatment.
Diagnosis relies on careful clinical assessment, identifying the specific anatomical location of tenderness. Ultrasound is valuable for identifying Morton’s neuroma and assessing plantar plate integrity. X-rays are obtained to rule out stress fracture, osteonecrosis and arthritis.
Conservative treatment is effective for most causes of metatarsalgia: offloading metatarsal pads or custom orthotics, appropriate footwear (wide toe box, cushioned sole), activity modification, and physiotherapy.
For Morton’s neuroma, an ultrasound-guided corticosteroid injection frequently provides long-lasting relief. Surgical excision of the neuroma is reserved for cases that fail injection therapy.
Surgical treatment of other causes (correcting hammertoe deformity, metatarsal osteotomy to equalise loading) is available for patients not responding to conservative management.
Dr Smith has written in more detail about this topic on his own site: metatarsalgia.